Massive galaxy clusters represent an ideal laboratory to test our models in a mass regime where structure formation is driven mainly by gravity. Furthermore, the properties of high redshift clusters can be compared with local samples to investigate the evolution and assembly of large structures across cosmic times. Within this context, we present the latest efforts to study the spatially resolved thermodynamic and hydrostatic mass profiles of 42 massive clusters detected at z>0.5 via the Sunyaev-Zel'dovich effect, using a method which optimally exploits information from XMM-Newton and Chandra observations for the z~1 objects. Leveraging the XMM-Newton’s photon collecting power and the superb Chandra resolution allows us to spatially resolve the profiles from the core to the outskirts, for the first time in such objects. Evolution properties are investigated by comparison with a local galaxy cluster sample. Finally, we discuss the current limitations of these studies and the present and future efforts to increase our knowledge on such objects.